Exact incidence is unknown, but it is estimated at 1 in 10,000
SIGNS AND SYMPTOMS
- Low birth weight (usually under 5 pounds/2.5 kilograms)
- Delayed growth and small stature
- Developmental delay
- Limb differences (missing limbs or portions of limbs)
- Small head size(microcephaly)
- Thick eyebrows, which typically meet at midline
- Long eyelashes
- Short upturned nose and thin downturned lips
- Excessive body hair
- Small hands and feet
- Small widely spaced teeth
- Low-set ears
- Hearing impairments
- Vision abnormalities
- Partial joining of the second and third toes
- Incurved 5th finger
- Gaestrooesophageal reflux
- Seizures
- Heart defect
- Cleft palate
- Feeding problems
- Hypoplastic genitalia
TREATMENT
- Physical therapy
- Neurodevelopmental therapy
- Occupational therapy
- Postural correction
- Kinesio taping
- Sensory integration therapy
- Aids and appliances support (orthosis)
- Pre-vocational training
- Special education(remedial tutoring)
- Parents counselling
- Feeding training